The structure of DNA
Grade 9 Science Worksheet - Building Confidence

Circle the best answer.
Ari labels a paper model of DNA. Arrow W points to the long outer line of the top strand. What is W?
- The sugar-phosphate backbone, a chain of sugars and phosphates
- A line of hydrogen bonds holding the two strands together
- A row of bases, because the bases form the outer lines
- A stack of base pairs, one resting on the next one
Esme outlines one unit on the model. Outline Y circles a five-sided shape, a round shape and a lettered block, joined together. What is Y?
Ladder (model, not to scale). Top strand bases G, C, A, T; bottom strand bases C, G, T, A. Outline Y circles one unit on the top strand: a five-sided shape, a round shape and a lettered block joined together. Ladder (model, not to scale). Top strand bases G, C, A, T; bottom strand bases C, G, T, A. Outline Y circles one unit on the top strand: a five-sided shape, a round shape and a lettered block joined together. Y G C A T C G T A - A base pair: two bases, one from each strand
- A nucleotide: one sugar, one phosphate and one base
- A backbone: a long chain of sugars and phosphates
- A hydrogen bond: a weak link between two bases
Jun fills in a paper ladder. Which base goes in the blank, directly under adenine (A)?
Ladder (model, not to scale). Top strand bases A, G, C, T. Bottom strand bases ?, C, G, A. The ? is directly under A. Ladder (model, not to scale). Top strand bases A, G, C, T. Bottom strand bases ?, C, G, A. The ? is directly under A. model, not to scale Top strand Bottom strand A G C T ? C G A - Thymine (T), the partner of adenine
- Adenine (A), because matching letters go together
- Guanine (G), because both bases have double rings
- Cytosine (C), the partner of guanine
Kira fills in a second paper ladder. Which base goes in the blank, directly under cytosine (C)?
Ladder (model, not to scale). Top strand bases T, C, G, A. Bottom strand bases A, ?, C, T. The ? is directly under C. Ladder (model, not to scale). Top strand bases T, C, G, A. Bottom strand bases A, ?, C, T. The ? is directly under C. model, not to scale Top strand bases Bottom strand bases T C G A A ? C T - Cytosine (C), because matching letters go together
- Thymine (T), because both bases have single rings
- Adenine (A), the partner of thymine
- Guanine (G), the partner of cytosine
Ladder (model, not to scale). Luz completes the bottom strand under A, C, G. Which three bases fill the blanks, left to right?
Ladder (model, not to scale). Top strand bases A, C, G. Bottom strand bases ?, ?, ?, each directly under a top base. Ladder (model, not to scale). Top strand bases A, C, G. Bottom strand bases ?, ?, ?, each directly under a top base. Top strand Bottom strand A C G ? ? ? - C, G, T
- A, C, G
- T, G, C
- G, T, A
Two drawings (not to scale). Milo compares two drawings of the dotted hydrogen bonds between paired bases. Which case is correct?
Two drawings (not to scale). Columns: pair, Case P, Case Q. Case P: the A–T pair has 2 dotted links and the C–G pair has 3 dotted links. Case Q: the A–T pair has 3 dotted links and the C–G pair has 2 dotted links. Two drawings (not to scale). Columns: pair, Case P, Case Q. Case P: the A–T pair has 2 dotted links and the C–G pair has 3 dotted links. Case Q: the A–T pair has 3 dotted links and the C–G pair has 2 dotted links. pair Case P Case Q A-T A T A T C-G C G C G - Case P, because the two kinds of pair have the same number of bonds
- Case Q, because a pair with a double ring has 3 bonds
- Case P, because A–T has 2 bonds and C–G has 3
- Case Q, because A–T has 3 bonds and C–G has 2
Two drawings of rungs (not to scale). Noah checks which drawing pairs the bases correctly. Which case is correct?
Two drawings of rungs (not to scale). Columns: base, Case 1, Case 2. Case 1: A is paired with G, and C is paired with T. Case 2: A is paired with T, and C is paired with G. Two drawings of rungs (not to scale). Columns: base, Case 1, Case 2. Case 1: A is paired with G, and C is paired with T. Case 2: A is paired with T, and C is paired with G. base Case 1 Case 2 A C A G C T A T C G - Case 2, because A pairs with T and C pairs with G
- Case 1, because bases with matching ring counts pair up
- Case 1, because A pairs with G and C pairs with T
- Case 2, because each rung joins two single-ring bases
“Two drawings (not to scale). Columns:” Pia compares two drawings of a short stretch of DNA. Which case puts the parts in the right places?
Two drawings (not to scale). Columns: part, Case A, Case B. Case A: the bases are on the two outer edges and the sugar-phosphate chains are in the middle. Case B: the sugar-phosphate chains are on the two outer edges and the bases meet in the middle. Two drawings (not to scale). Columns: part, Case A, Case B. Case A: the bases are on the two outer edges and the sugar-phosphate chains are in the middle. Case B: the sugar-phosphate chains are on the two outer edges and the bases meet in the middle. part Case A Case B bases sugar-phosphate chains sugar-phosphate chains bases - Case A, because the bases form the long outer lines
- Case B, because the bases meet inside the chains
- Case A, because the bases need to be outside to pair up
- Case B, because the phosphates join the two strands in the middle
Tala reads the same history card. Where did Watson and Crick get X-ray data for their double-helix model?
History card (real dates). 1952: Rosalind Franklin with Raymond Gosling, at King's College London, make an X-ray photo of the B form of DNA, labeled 51. 1953: James Watson and Francis Crick, at the University of Cambridge, publish a double-helix model built with Franklin's X-ray data on 25 April; Franklin and Gosling publish a paper in the same issue of Nature. 1962: Francis Crick, James Watson and Maurice Wilkins receive the Nobel Prize in Physiology or Medicine. History card (real dates). 1952: Rosalind Franklin with Raymond Gosling, at King's College London, make an X-ray photo of the B form of DNA, labeled 51. 1953: James Watson and Francis Crick, at the University of Cambridge, publish a double-helix model built with Franklin's X-ray data on 25 April; Franklin and Gosling publish a paper in the same issue of Nature. 1962: Francis Crick, James Watson and Maurice Wilkins receive the Nobel Prize in Physiology or Medicine. History card (real dates) 1952 1953 1954 1955 1956 1957 1958 1959 1960 1961 1962 1952 1953 1962 1952: Rosalind Franklin with Raymond Gosling, at King's College London, make an X-ray photo of the B form of DNA, labeled 51. 1953: James Watson and Francis Crick, at the University of Cambridge, publish a double-helix model built with Franklin's X-ray data on 25 April; Franklin and Gosling publish a paper in the same issue of Nature. 1962: Francis Crick, James Watson and Maurice Wilkins receive the Nobel Prize in Physiology or Medicine. - They used no X-ray data and built the model from parts
- From the 1962 prize paper, written after the model
- From Franklin's X-ray work at King's College London
- From an X-ray photo they took themselves at Cambridge
Card of base-pair facts (Data: OpenStax Biology 2e). Columns: base pair, hydrogen bonds. A–T: 2. C–G: 3. Zee reads a card of facts about base pairs. How many hydrogen bonds join a C–G pair?
- 5 hydrogen bonds
- 1 hydrogen bond
- 2 hydrogen bonds
- 3 hydrogen bonds