Homeostasis: how the body keeps things steady
Grade 9 Science Worksheet - Challenge Me

Circle the best answer.
A meal is eaten just after minute 0, and the normal range is about 70 to 100 mg/dL. Luz reads the meal card. At which minute does it show the strongest response to a low glucose level?
- Minute 60: the glucose level equals the set point of 100, so no hormone acts
- Minute 30: insulin is highest at 9 while the glucose level is highest at 125
- Minute 120: glucagon is 4 and the glucose level is 85, the middle of the card
- Minute 180: glucagon is highest at 7 while the glucose level is lowest at 70
The run lasts from minute 0 to minute 15, and the set point is about 37 °C. Kira reads the exercise card. After minute 15, temperature, skin blood flow and sweat all fall. What does this show about the loop?
- The stimulus shrank as the temperature fell, so the response eased
- The loop switched off because the temperature reached exactly 37 °C
- The response grew stronger as the temperature fell, pushing it further
- The set point fell, so less cooling was needed
Bo edits a model of the body temperature loop: the arrow from the control center to the effectors is cut. Body temperature then rises above 37 °C. What does the model predict?
- The temperature stays above the set point, because the effectors get no order
- The temperature rises faster, because the cut arrow makes the loop positive
- The temperature stays at exactly 37 °C, because the set point holds it there
- The temperature falls back, because the sensors make the response themselves
In a model, Jun changes the loop so that, after a meal, the pancreas releases glucagon instead of insulin. What happens to the glucose level?
Feedback loop (model, not to scale) for the glucose level, normal range about 70 to 100 mg/dL. Stimulus: the glucose level rises after a meal. Sensor: cells of the pancreas. Control center: the pancreas, set to release glucagon instead of insulin. Effector: liver cells that release glucose. Response: ? Feedback loop (model, not to scale) for the glucose level, normal range about 70 to 100 mg/dL. Stimulus: the glucose level rises after a meal. Sensor: cells of the pancreas. Control center: the pancreas, set to release glucagon instead of insulin. Effector: liver cells that release glucose. Response: ? Feedback loop (model, not to scale) normal range about 70 to 100 mg/dL Stimulus: the glucose level rises after a meal Sensor: cells of the pancreas Control center: the pancreas, set to release glucagon instead of insulin Effector: liver cells that release glucose Response: ? - It stays the same, because glucagon has no effect after a meal
- It rises further, because glucagon raises the glucose level
- It falls, because negative feedback lowers a level
- It stays inside the range, because the loop still reverses the change
“model, not to scale” Noah tests a model of the ADH loop when body fluid volume is low. Which change would make the model lose less water?
Feedback loop (model, not to scale) for body fluid volume. Stimulus: body fluid volume is low. Control center: the hypothalamus and posterior pituitary, which make and release ADH. Effector: the kidneys, which take back water when ADH reaches them. Response: less water is lost. Feedback loop (model, not to scale) for body fluid volume. Stimulus: body fluid volume is low. Control center: the hypothalamus and posterior pituitary, which make and release ADH. Effector: the kidneys, which take back water when ADH reaches them. Response: less water is lost. Feedback loop for body fluid volume Stimulus body fluid volume is low Control center the hypothalamus and posterior pituitary make and release ADH Effector the kidneys take back water when ADH reaches them Response less water is lost - Less ADH reaches the kidneys, so they take back more water
- The kidneys release ADH, so the pituitary takes back more water
- More ADH reaches the kidneys, so they take back more water
- More ADH reaches the kidneys, so they release more water
Read this first
Use this
Notebook (model data), 4 rows. Columns: line, what it says. 1, Temperature sensors detect a rise in body temperature. 2, The control center compares the value with the set point. 3, The sensors then make the response, such as sweating. 4, The response brings body temperature back toward the set point.
Ari reviews a classmate's notebook on the body temperature loop. Exactly one line is wrong. Which line, and why?
- Line 4, because the response makes the temperature rise more
- Line 1, because the control center detects a rise in temperature
- Line 3, because the effectors, not the sensors, make the response
- Line 2, because the sensors compare the value with the set point
Use this
Notebook (model data), 4 rows. Columns: line, what it says. 1, After a meal the glucose level rises. 2, The pancreas releases insulin. 3, Insulin raises the glucose level so cells have fuel. 4, Between meals, glucagon is released when the level falls.
Tala reviews a classmate's notebook on the glucose level. Exactly one line is wrong. Which line, and why?
- Line 2, because the pancreas releases glucagon after a meal
- Line 4, because a negative loop cannot raise a level
- Line 1, because the glucose level falls after a meal
- Line 3, because insulin lowers the glucose level
Use this
Notebook (model data), 4 rows. Columns: line, what it says. 1, In a negative loop, the response reverses the change. 2, In a positive loop, the response pushes the change further. 3, A positive loop in the body runs until it reaches an end point. 4, Positive feedback is the usual kind in the body, and negative is rare.
Pia reviews a classmate's notebook on kinds of feedback. Exactly one line is wrong. Which line, and why?
- Line 1, because a negative loop lowers a level instead of reversing a change
- Line 3, because a positive loop has no end point
- Line 2, because a positive loop reverses the change that started it
- Line 4, because negative feedback is the usual kind in the body
Use this
Two models (not to scale). Model 1, body temperature: when body temperature rises above about 37 °C, sweat is released and the temperature falls back. Model 2, clotting boxes: early clotting factor activates next clotting factor, which activates thrombin; thrombin activates more early clotting factors until a clot is complete.
Ren compares the body temperature loop with the clotting boxes. Which statement compares them correctly?
- Both models push their change further until an end point, so both are positive
- Model 1 reverses its change, while Model 2 adds to its change until an end point
- Model 1 is negative, while Model 2 is the helpful positive loop that keeps the body steady
- Model 1 is harmful because it is negative, while Model 2 is the helpful kind
Use this
Two loops (model, not to scale) for the glucose level, normal range about 70 to 100 mg/dL. Loop 1: the level rises above the range, insulin is released, and the level falls. Loop 2: the level falls below the range, glucagon is released, and the level rises.
Tala claims the glucose system is not negative feedback, because glucagon raises the level. Is the claim sound?
- No: raising a low level helps the body, so Loop 2 is positive feedback
- No: each loop reverses a change, so raising a low level is also negative feedback
- Yes: negative feedback lowers a level, and glucagon raises it
- Yes: the glucagon loop helps the body, and negative feedback is the harmful kind