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9th grade How cell parts work together to make and ship a protein worksheet

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How cell parts work together to make and ship a protein

Grade 9 Science Worksheet - Challenge Me

NameDate

Circle the best answer.

  1. Read this first

    Use the table

    Cell cutaway (animal cell, model, not to scale). Letter A marks the rough ER (the flat folded sacs studded with tiny dots, joined to the wall of the large round body). Letter B marks the transport vesicle (a small bubble between the dotted sacs and the stack of curved smooth sacs). Letter C marks the Golgi apparatus (the stack of curved smooth sacs, away from the dotted sacs). Route in order: nucleus, nuclear pore, rough ER, transport vesicle, Golgi apparatus, secretory vesicle, plasma membrane. Pulse-chase card, read about only. Where most of the label is found (model data)

    cellat 20 minutesat 60 minutes
    normal cellGolgi apparatusoutside the cell
    changed celltransport vesiclestransport vesicles
  2. Ari sees that in the changed cell one job fails. Use the cutaway and the card. Which job fails?

    • The nucleus is not building the protein, so no label moves on
    • The Golgi apparatus is not building the protein from amino acids
    • Vesicles are not delivering protein from the rough ER to the Golgi
    • Secretory vesicles are not fusing with the plasma membrane at the cell edge
  3. Bo follows proteins M and K, which travel the same route. What does the card show about the end of it?

    • Both leave the Golgi in vesicles; M is released and K joins the membrane
    • The vesicle carrying K stays fixed at the cell edge as a permanent part of the cell
    • K is built in the Golgi apparatus, which is why it joins the membrane
    • K skips the Golgi and uses no vesicle to reach the membrane
  4. Esme compares three gland cells with the route in the cutaway. Which statement does the card support?

    • Release depends on the rough ER, since each part does its job on its own
    • Release is highest in Z, since Z has the most rough ER
    • Release depends on the Golgi apparatus, since the Golgi builds the protein
    • More rough ER and Golgi go with more release, as the route uses both
  5. Jun sees no label outside the cell at 20 minutes, though the protein was made by 5 minutes. Why does this fit the route?

    • The nucleus holds the finished protein until 60 minutes, then releases it
    • The rough ER works alone, so it needs 60 minutes to send it out
    • The protein is still on its way, passing several parts before release
    • A vesicle is a fixed part that stores the protein until 60 minutes
  6. Kira sees that the changed cell makes the protein but releases almost none. Which explanation fits the card?

    • Vesicles are not carrying protein from the Golgi to the membrane
    • The Golgi apparatus is not building enough of the protein to send on
    • Transport vesicles are not delivering protein from the rough ER
    • The nucleus is holding the finished protein inside and not releasing it
  7. Notebook route (not to scale), five lines

    Line 1 the nucleus (A), line 2 the Golgi apparatus (B), line 3 the rough ER (C), line 4 a secretory vesicle (D), line 5 the plasma membrane (E). Letter A marks the large round body near the middle, with a double wall. Letter B marks the stack of curved smooth sacs, away from the dotted sacs. Letter C marks the flat folded sacs studded with tiny dots, joined to the wall of the large round body. Letter D marks a small bubble between the stack of curved sacs and the cell edge. Letter E marks the thin outer boundary of the cell.

  8. Milo's notebook lists the route of a protein that leaves the cell. Which line has a flaw, and why?

    • Line 4 is wrong: a vesicle is a fixed part, so it cannot sit between two stops
    • Line 1 is wrong: the nucleus builds the protein, so the rough ER is not needed
    • Lines 2 and 3 are swapped: the rough ER builds the protein before the Golgi
    • Line 2 is right: the Golgi builds the protein, so it comes before the rough ER
  9. Use the table

    Pulse-chase card, read about only. Where the label was found (model data)

    minutes after labelingmost label found in
    5rough ER
    25Golgi apparatus
  10. Noah's class saw label in the Golgi apparatus at 25 minutes and concluded the Golgi built the protein. What is the flaw?

    • No flaw: label found in a part shows that part built the protein
    • The label was in the rough ER first, so the protein reached the Golgi already built
    • The label should have been in the nucleus first, since the nucleus builds proteins
    • The Golgi cannot be tested, since each part works alone
  11. Rough ER counted in one slice of each cell (model data)

    cellrough ER sacs
    gland cell44
    muscle cell10
  12. Pia's class counted rough ER in one gland cell and one muscle cell, then said every gland cell has more. Which flaw is in the conclusion?

    • The nucleus was not counted, and the nucleus builds the proteins
    • The counts do not matter, because each part works alone and the cell type cannot change them
    • Only one cell of each type was counted, so more cells are needed
    • Rough ER cannot be counted, because it is too small to see
  13. Tala says the Golgi apparatus could still pack proteins for release if the rough ER stopped making them. Which response is best?

    • Disagree: the vesicles are fixed parts that would keep delivering protein
    • Disagree: the Golgi packages proteins that arrive from the rough ER
    • Agree: the Golgi apparatus builds its own proteins to pack
    • Agree: each part works alone, so the Golgi needs no protein from the rough ER
  14. Cell cutaway (plant cell, model, not to scale). Zee says a leaf cell has chloroplasts (A), so its mitochondria (B) are not needed. Which response fits?

    • Agree: the chloroplast works alone and supplies the cell’s energy by itself
    • Agree: plant cells have no mitochondria
    • Disagree: mitochondria make the sugar that chloroplasts use
    • Disagree: mitochondria use the chloroplasts’ sugar to provide ATP
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9th grade How cell parts work together to make and ship a protein worksheet – printable
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About this worksheet

How cell parts work together to make and ship a protein. Every version has 10 questions, and the answer key prints on the second page.

What your child will learn

  • I can follow a protein that leaves the cell from start to finish: mRNA leaves the nucleus through a pore, ribosomes on the rough ER build the protein, the rough ER folds and modifies it, a transport vesicle carries it to the Golgi apparatus, the Golgi modifies, tags and packages it, and a secretory vesicle fuses with the plasma membrane to release it.
  • I can name each lettered part on the route from how it looks, and say what job it does for the protein.
  • I can say which part builds the protein (ribosomes on the rough ER) and which part only receives and packages it (the Golgi), and what the nucleus sends out (mRNA).
  • I can say what a vesicle is: a small bubble of membrane that buds off, delivers, and fuses with the next membrane.
  • I can predict where a protein is held up when one part stops working.
  • I can read a read-about pulse-chase card (model data with times) and trace where the label goes next.

Standard: supports HS-LS1-1

Words to know

nucleus: The part that houses the cell's DNA

nuclear pore: A gap in the nucleus wall that lets RNA pass

mRNA: A message carried from the nucleus to the ribosomes

ribosome: A tiny part that builds proteins

rough ER: Folded sacs studded with ribosomes; it folds and modifies new proteins

transport vesicle: A bubble that carries a protein from the rough ER to the Golgi

Golgi apparatus: A stack of sacs that modifies, tags and packages proteins

secretory vesicle: A bubble that carries a packaged protein to the plasma membrane

Common mistakes

Your child thought the Golgi apparatus builds proteins. Ribosomes build them; the Golgi receives, modifies, tags and packages them. Ask your child which part builds the protein and which part packages it.

Your child thought the nucleus builds proteins. The nucleus holds the DNA and sends mRNA out through its pores; ribosomes build the protein. Ask your child what leaves the nucleus.

Your child put the stops of the protein route in the wrong order. The order is nucleus, rough ER, vesicle, Golgi apparatus, vesicle, plasma membrane. Ask your child to say the route out loud, like a delivery path.

Questions parents ask

What is the most common mistake with how cell parts work together to make and ship a protein?

Your child thought the Golgi apparatus builds proteins. Ribosomes build them; the Golgi receives, modifies, tags and packages them. Ask your child which part builds the protein and which part packages it.

Are these 9th grade science worksheets free to print?

Yes. All 6 printable versions at each level are free to print, with the answer key, and no account is needed.

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