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9th grade How the body defends itself: immunity, vaccines and antibiotics worksheet

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How the body defends itself: immunity, vaccines and antibiotics

Grade 9 Science Worksheet

NameDate

Circle the best answer.

  1. Read this first

    Use this

    Map of the body's defenses (model, not to scale). Arrows, each marked with what it carries: microbe to skin and mucus, meets a barrier; skin and mucus to inflammation and fever, a microbe gets past; inflammation and fever to phagocytes, calls in; phagocytes to T cells, shows antigen pieces; T cells to B cells, sends an activation signal; B cells to antibodies, make; B cells to memory cells, some become.

  2. Bo follows the map after phagocytes engulf a microbe. They show antigen pieces to the next cells. Which cells are next, and what do they do?

    • T cells, which signal B cells to act
    • B cells, which make antibodies at once
    • Antibodies, which bind the antigen pieces
    • Memory cells, which make antibodies at once
  3. Use this

    Map of how a vaccine prepares the body (model, not to scale). Arrows, each marked with what it carries: vaccine to phagocytes, antigen pieces; phagocytes to T cells, shows antigen pieces; T cells to B cells, sends an activation signal; B cells to antibodies, make; B cells to memory cells, some become.

  4. Esme follows the map of how a vaccine prepares the body. After B cells are activated, which two products follow?

    • Antibodies, and memory cells that stay
    • Antibodies alone, with no cells left for next time
    • Phagocytes, and antigen pieces
    • Antibodies, and phagocytes that stay for next time
  5. Jun reads the three lines card and sorts a case. Tears wash microbes away from the surface of the eye. Which line is this?

    • Specific defenses, which are ready before any microbe arrives
    • Second line, the response inside the body
    • First line, the barriers at the body surface
    • Not a defense, because tears just keep the eye wet
  6. Kira reads the three lines card and sorts a case. A rise in body temperature slows the growth of some microbes. Which line is this?

    Use the picture in question 3.

    • Specific defenses, the line that acts first
    • Not a defense, because temperature does not affect microbes
    • First line, the barriers at the body surface
    • Second line, the response inside the body
  7. Use this

    Two types of immunity card (CDC facts), 2 rows. Columns: type, where the antibodies come from, timing. active, the person's own B cells, after an infection or a vaccine, takes longer to develop and lasts longer. passive, another person or an animal, protects at once and fades within weeks or months.

  8. Luz reads the card on two types of immunity. A vaccine's antigen leads a person's own B cells to make antibodies and memory cells. Which type is this?

    • Active, because the person's own cells make the antibodies
    • Active, because the protection starts at once
    • Passive, because the protection lasts for years
    • Passive, because the vaccine supplies the antibodies
  9. Milo reads a graph of antibody level after a vaccine with antigen X. At day 35 a microbe with antigen X arrives. Which prediction fits?

    • Antibodies rise quickly and high, because memory cells formed after the vaccine
    • Antibodies rise slowly again, because the vaccine left no memory
    • Antibodies stay low, because the vaccine supplied antibodies that are used up
    • Antibodies rise quickly and high, because vaccine antibodies fit any microbe
  10. Use this

    Two types of immunity card (CDC facts), 2 rows. Columns: type, where the antibodies come from, timing. active, the person's own B cells, after an infection or a vaccine, takes longer to develop and lasts longer. passive, another person or an animal, protects at once and fades within weeks or months.

  11. Pia reads the card on two types of immunity. A person has passive protection that began at day 0. Which prediction fits for day 365?

    • The protection has faded, because the antibodies came from another source
    • The protection has not begun, because passive immunity takes weeks to start
    • The protection is still strong, because passive immunity outlasts active immunity
    • The protection is stronger, because the antibodies multiply in the person
  12. Antibody response card (model data)

    exposureantibodies first rise (days after the exposure)peak level (arbitrary units)
    first1230
    second4300
  13. Ren reads an antibody response card. How many days sooner did antibodies first rise after the second exposure than after the first?

    • 4 days
    • 16 days
    • 12 days
    • 8 days
  14. Vaccine facts card (CDC and WHO facts)

    sourcefact
    CDCCDC monitors the safety of licensed vaccines through 4 systems that work together
    WHOno single vaccine gives 100 percent protection
  15. Tala reads a vaccine facts card from CDC and WHO. Which statement do the numbers on the card support?

    • Licensed vaccines are watched by 1 system, and each gives 100 percent protection
    • Licensed vaccines are watched by 4 systems, so each gives 100 percent protection
    • Safety checks end once a vaccine is licensed, so 0 systems watch it
    • Licensed vaccines are watched by 4 systems, and none gives 100 percent protection
  16. Community card (model data)

    grouppeople
    immune200
    not immune50
    whole community250
  17. Zee reads a community card. What percent of the people in the whole community are immune?

    • 80 percent
    • 25 percent
    • 125 percent
    • 20 percent
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9th grade How the body defends itself: immunity, vaccines and antibiotics worksheet – printable
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About this worksheet

The immune system and vaccines: three lines of defense, antibodies, memory cells and antibiotics. Every version has 10 questions, and the answer key prints on the second page.

What your child will learn

  • I can name the three lines of defense and say what is in each: skin and mucus (first line); inflammation, fever and phagocytes (second line); B cells, antibodies, T cells and memory cells (specific defenses).
  • I can say the first line is already in place, the second line works inside the body, and the specific defenses take days the first time a microbe is met.
  • I can say an antigen is a part of a microbe that the immune system responds to, and an antibody is a protein with a binding site shaped to match one antigen, so an antibody for one antigen does not fit a very different one.
  • I can trace the path on the map: phagocytes show antigen pieces to T cells, T cells signal B cells, B cells make antibodies, and some B cells become memory cells.
  • I can read a model graph of antibody level against days and say that a second exposure to the same antigen gives a response that starts sooner and reaches a higher level than the first, because memory cells are already in place. I can also say a different antigen starts a new, slower first response.
  • I can say a vaccine contains an antigen (a weakened or inactivated microbe, pieces of it, or a treated toxin), the person's own cells make the antibodies and memory cells, and some vaccines need more than one dose.

Standard: supports HS-LS1-2

Words to know

microbe: A living thing too small to see without a microscope, such as a bacterium

barrier: Something that blocks microbes at the body surface, such as skin or mucus

mucus: A sticky layer that traps microbes and is swept out of the body

inflammation: A response at one spot that brings in white blood cells

fever: A rise in body temperature that slows the growth of some microbes

phagocyte: A white blood cell that engulfs and digests microbes

antigen: A part of a microbe, or other foreign molecule, that the immune system responds to

antibody: A protein with a binding site that matches the shape of one antigen

Common mistakes

Your child thought the specific defenses, such as antibodies, act first. Skin and mucus are already in place, the second line follows, and the specific defenses take days the first time. Ask your child which defense is in place before any microbe arrives.

Your child thought one antibody fits any antigen. Each antibody has a binding site that matches the shape of one antigen. Ask your child why an antibody for one microbe would not bind a very different one.

Your child thought the second response is the same as the first. Memory cells make the second response start sooner and reach a higher level. Ask your child what the memory cells change.

Questions parents ask

What is the most common mistake with how the body defends itself: immunity, vaccines and antibiotics?

Your child thought the specific defenses, such as antibodies, act first. Skin and mucus are already in place, the second line follows, and the specific defenses take days the first time. Ask your child which defense is in place before any microbe arrives.

Are these 9th grade science worksheets free to print?

Yes. All 6 printable versions at each level are free to print, with the answer key, and no account is needed.

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