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9th grade How the body defends itself: immunity, vaccines and antibiotics worksheet

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How the body defends itself: immunity, vaccines and antibiotics

Grade 9 Science Worksheet - Challenge Me

NameDate

Circle the best answer.

  1. Ari reads a graph for a vaccine at day 0 and a microbe with the same antigen at day 28. Which statement combines what the graph shows with why?

    • The level reaches 70 within 7 days, above the first peak of 6, since memory cells formed
    • The level stays near 2 after day 28, since vaccine antibodies already cover the antigen
    • The rise after day 28 matches the rise after day 0, since each exposure starts from nothing
    • The rise after day 28 is slower than after day 0, since the vaccine used up the antibodies
  2. Microbe card (model data), 2 rows. Columns: microbe, antigen on its surface. P, X. Q, Y. Bo reads a microbe card. A vaccine with antigen X was given earlier, and antigen Y is not similar to X. Which statement fits both microbes?

    • A slow response to both microbes, since each exposure starts from nothing
    • A fast response to microbe P only, since its antigen matches the memory cells
    • A fast response to microbe Q only, since a new antigen wakes the memory cells
    • A fast response to both microbes, since memory cells match any antigen
  3. Esme reads a defense timing card. Which statement combines the lines of defense with the timing on the card?

    • Antibodies start first, and phagocytes start after 10 days
    • Skin and mucus start after 1 day, and antibodies start after 3 days the first time
    • Phagocytes start after 1 day, and antibodies start sooner on a repeat exposure
    • Antibodies start after 10 days on each exposure, so specific defenses cannot speed up
  4. Jun reads a shape card. A microbe's surface changes from antigen X to a new antigen Z. Which prediction fits the next response?

    • A fast, high rise like a second exposure, because memory cells' antibodies fit any tip
    • A slow, low rise like a first exposure, since the antibodies do not fit square tips
    • A fast, high rise, because the microbe is still the same kind of microbe as before
    • No rise, because the first response cleared that microbe from the body for good
  5. Kira reads a graph for one vaccine dose at day 0. In the model, a second dose is given at day 28. Which prediction fits the response after it?

    • The same as after dose 1, because memory cells reset after each dose of the vaccine
    • Lower than after dose 1, because the first dose used up the antigen in the vaccine
    • Higher than after dose 1, because dose 2 delivers ready-made antibodies
    • Higher and faster than after dose 1, because dose 2 acts like a second exposure
  6. Read this first

    Use this

    Notebook (model data), 4 rows. Columns: line, what it says. 1, A vaccine contains an antigen from a microbe. 2, After a vaccine, the body's own B cells make antibodies. 3, Memory cells can make a later response faster. 4, A vaccine gives the person ready-made antibodies.

  7. Noah reviews a classmate's notebook on vaccines. Exactly one line is wrong. Which line, and why?

    • Line 1, because a vaccine contains no antigen
    • Line 2, because the vaccine supplies the antibodies, not the B cells
    • Line 3, because a vaccine cannot lead to memory cells
    • Line 4, because the body makes its own antibodies after a vaccine
  8. Use this

    Notebook (model data), 4 rows. Columns: line, what it says. 1, Antibiotics treat certain infections caused by bacteria. 2, Antibiotics work on the viruses that cause a cold or the flu. 3, Bacteria that survive an antibiotic can multiply and spread their resistance. 4, A vaccine prepares memory cells, which is different from what an antibiotic does.

  9. Pia reviews a classmate's notebook on antibiotics. Exactly one line is wrong. Which line, and why?

    • Line 2, because antibiotics do not work on viruses
    • Line 3, because resistance is a trait of people, not of bacteria
    • Line 4, because a vaccine and an antibiotic do the same job
    • Line 1, because antibiotics treat any kind of germ
  10. Ren reads a graph of antibody level after exposures at day 0 and day 28. Which statement does the graph support?

    • The second peak, 100, was 10 times the first peak, 10, but came later after its exposure
    • The second peak, 100, was 90 times the first peak, 10, and came sooner after its exposure
    • The second peak, 100, matched the first peak, and came sooner after its exposure
    • The second peak, 100, was 10 times the first peak, 10, and came sooner after its exposure
  11. Two communities card (model data)

    communitypeopleimmune people
    A400200
    B400360
  12. Tala reads a card on two communities. Which statement does the card support?

    • Community B is 90 percent immune, so a microbe meets fewer people it can spread to
    • Community A is better protected, since 200 immune people is a smaller number to protect
    • In both communities each immune person is protected alone, so spread is equal
    • Community B is fully protected, so each person in it is safe from the microbe
  13. Bacteria count card (model data)

    stepbacteriabacteria with the resistance trait
    before the antibiotic1,00010
    just after the antibiotic1010
    after regrowth640640
  14. Zee reads a count card for bacteria and one antibiotic. Which statement does the card support?

    • The person's own cells became resistant to the antibiotic, so 640 bacteria grew back
    • The 10 bacteria that remained had the trait before the antibiotic and then multiplied
    • The antibiotic gave the resistance trait to the 10 bacteria that remained in the sample
    • The antibiotic cleared the viruses too, so just the bacteria with the trait were left
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9th grade How the body defends itself: immunity, vaccines and antibiotics worksheet – printable
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About this worksheet

The immune system and vaccines: three lines of defense, antibodies, memory cells and antibiotics. Every version has 10 questions, and the answer key prints on the second page.

What your child will learn

  • I can name the three lines of defense and say what is in each: skin and mucus (first line); inflammation, fever and phagocytes (second line); B cells, antibodies, T cells and memory cells (specific defenses).
  • I can say the first line is already in place, the second line works inside the body, and the specific defenses take days the first time a microbe is met.
  • I can say an antigen is a part of a microbe that the immune system responds to, and an antibody is a protein with a binding site shaped to match one antigen, so an antibody for one antigen does not fit a very different one.
  • I can trace the path on the map: phagocytes show antigen pieces to T cells, T cells signal B cells, B cells make antibodies, and some B cells become memory cells.
  • I can read a model graph of antibody level against days and say that a second exposure to the same antigen gives a response that starts sooner and reaches a higher level than the first, because memory cells are already in place. I can also say a different antigen starts a new, slower first response.
  • I can say a vaccine contains an antigen (a weakened or inactivated microbe, pieces of it, or a treated toxin), the person's own cells make the antibodies and memory cells, and some vaccines need more than one dose.

Standard: supports HS-LS1-2

Words to know

microbe: A living thing too small to see without a microscope, such as a bacterium

barrier: Something that blocks microbes at the body surface, such as skin or mucus

mucus: A sticky layer that traps microbes and is swept out of the body

inflammation: A response at one spot that brings in white blood cells

fever: A rise in body temperature that slows the growth of some microbes

phagocyte: A white blood cell that engulfs and digests microbes

antigen: A part of a microbe, or other foreign molecule, that the immune system responds to

antibody: A protein with a binding site that matches the shape of one antigen

Common mistakes

Your child thought the specific defenses, such as antibodies, act first. Skin and mucus are already in place, the second line follows, and the specific defenses take days the first time. Ask your child which defense is in place before any microbe arrives.

Your child thought one antibody fits any antigen. Each antibody has a binding site that matches the shape of one antigen. Ask your child why an antibody for one microbe would not bind a very different one.

Your child thought the second response is the same as the first. Memory cells make the second response start sooner and reach a higher level. Ask your child what the memory cells change.

Questions parents ask

What is the most common mistake with how the body defends itself: immunity, vaccines and antibiotics?

Your child thought the specific defenses, such as antibodies, act first. Skin and mucus are already in place, the second line follows, and the specific defenses take days the first time. Ask your child which defense is in place before any microbe arrives.

Are these 9th grade science worksheets free to print?

Yes. All 6 printable versions at each level are free to print, with the answer key, and no account is needed.

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