How the body defends itself: immunity, vaccines and antibiotics
Grade 9 Science Worksheet - Challenge Me

Circle the best answer.
Ari reads a graph for a vaccine at day 0 and a microbe with the same antigen at day 28. Which statement combines what the graph shows with why?
- The level reaches 70 within 7 days, above the first peak of 6, since memory cells formed
- The level stays near 2 after day 28, since vaccine antibodies already cover the antigen
- The rise after day 28 matches the rise after day 0, since each exposure starts from nothing
- The rise after day 28 is slower than after day 0, since the vaccine used up the antibodies
Microbe card (model data), 2 rows. Columns: microbe, antigen on its surface. P, X. Q, Y. Bo reads a microbe card. A vaccine with antigen X was given earlier, and antigen Y is not similar to X. Which statement fits both microbes?
- A slow response to both microbes, since each exposure starts from nothing
- A fast response to microbe P only, since its antigen matches the memory cells
- A fast response to microbe Q only, since a new antigen wakes the memory cells
- A fast response to both microbes, since memory cells match any antigen
Esme reads a defense timing card. Which statement combines the lines of defense with the timing on the card?
Defense timing card (model data), 4 rows. Columns: defense, line, starts after the microbe arrives. skin and mucus, first line, already in place. phagocytes, second line, 1 day. antibodies, first exposure, specific defenses, 10 days. antibodies, repeat exposure, specific defenses, 3 days. Defense timing card (model data), 4 rows. Columns: defense, line, starts after the microbe arrives. skin and mucus, first line, already in place. phagocytes, second line, 1 day. antibodies, first exposure, specific defenses, 10 days. antibodies, repeat exposure, specific defenses, 3 days. Defense timing card (model data) defense line starts after the microbe arrives skin and mucus first line already in place phagocytes second line 1 day antibodies first exposure, specific defenses 10 days antibodies repeat exposure, specific defenses 3 days - Antibodies start first, and phagocytes start after 10 days
- Skin and mucus start after 1 day, and antibodies start after 3 days the first time
- Phagocytes start after 1 day, and antibodies start sooner on a repeat exposure
- Antibodies start after 10 days on each exposure, so specific defenses cannot speed up
Jun reads a shape card. A microbe's surface changes from antigen X to a new antigen Z. Which prediction fits the next response?
Shape card (model data), 2 rows. Columns: antigen, tip shape, fits the memory cells' antibodies. old antigen X, triangle, yes. new antigen Z, square, no. Shape card (model data), 2 rows. Columns: antigen, tip shape, fits the memory cells' antibodies. old antigen X, triangle, yes. new antigen Z, square, no. antigen tip shape fits the memory cells' antibodies old antigen X triangle yes new antigen Z square no Shape card (model data), 2 rows. - A fast, high rise like a second exposure, because memory cells' antibodies fit any tip
- A slow, low rise like a first exposure, since the antibodies do not fit square tips
- A fast, high rise, because the microbe is still the same kind of microbe as before
- No rise, because the first response cleared that microbe from the body for good
Kira reads a graph for one vaccine dose at day 0. In the model, a second dose is given at day 28. Which prediction fits the response after it?
Model graph of antibody level after a first vaccine dose (model data). Time since the first dose (days) across, 0 to 42, a mark every 7. Antibody level (arbitrary units) up, 0 to 40, a mark every 10. Antibody level joins (0, 0), (7, 2), (14, 8), (21, 5), (28, 3). A second dose of the same vaccine is given at day 28. Model graph of antibody level after a first vaccine dose (model data). Time since the first dose (days) across, 0 to 42, a mark every 7. Antibody level (arbitrary units) up, 0 to 40, a mark every 10. Antibody level joins (0, 0), (7, 2), (14, 8), (21, 5), (28, 3). A second dose of the same vaccine is given at day 28. Model graph of antibody level after a first vaccine dose (model data) 0 7 14 21 28 35 42 0 10 20 30 40 Time since the first dose (days) Antibody level (arbitrary units) A second dose of the same vaccine is given at day 28 - The same as after dose 1, because memory cells reset after each dose of the vaccine
- Lower than after dose 1, because the first dose used up the antigen in the vaccine
- Higher than after dose 1, because dose 2 delivers ready-made antibodies
- Higher and faster than after dose 1, because dose 2 acts like a second exposure
Read this first
Use this
Notebook (model data), 4 rows. Columns: line, what it says. 1, A vaccine contains an antigen from a microbe. 2, After a vaccine, the body's own B cells make antibodies. 3, Memory cells can make a later response faster. 4, A vaccine gives the person ready-made antibodies.
Noah reviews a classmate's notebook on vaccines. Exactly one line is wrong. Which line, and why?
- Line 1, because a vaccine contains no antigen
- Line 2, because the vaccine supplies the antibodies, not the B cells
- Line 3, because a vaccine cannot lead to memory cells
- Line 4, because the body makes its own antibodies after a vaccine
Use this
Notebook (model data), 4 rows. Columns: line, what it says. 1, Antibiotics treat certain infections caused by bacteria. 2, Antibiotics work on the viruses that cause a cold or the flu. 3, Bacteria that survive an antibiotic can multiply and spread their resistance. 4, A vaccine prepares memory cells, which is different from what an antibiotic does.
Pia reviews a classmate's notebook on antibiotics. Exactly one line is wrong. Which line, and why?
- Line 2, because antibiotics do not work on viruses
- Line 3, because resistance is a trait of people, not of bacteria
- Line 4, because a vaccine and an antibiotic do the same job
- Line 1, because antibiotics treat any kind of germ
Ren reads a graph of antibody level after exposures at day 0 and day 28. Which statement does the graph support?
Model graph of antibody level after two exposures to one microbe (model data). Time since the first exposure (days) across, 0 to 49, a mark every 7. Antibody level (arbitrary units) up, 0 to 120, a mark every 20. Antibody level joins (0, 0), (7, 2), (14, 10), (21, 8), (28, 4), (35, 100), (42, 60), (49, 40). Exposures happen at day 0 and day 28. Model graph of antibody level after two exposures to one microbe (model data). Time since the first exposure (days) across, 0 to 49, a mark every 7. Antibody level (arbitrary units) up, 0 to 120, a mark every 20. Antibody level joins (0, 0), (7, 2), (14, 10), (21, 8), (28, 4), (35, 100), (42, 60), (49, 40). Exposures happen at day 0 and day 28. Model graph of antibody level after two exposures to one microbe (model data) 0 7 14 21 28 35 42 49 0 20 40 60 80 100 120 Time since the first exposure (days) Antibody level (arbitrary units) exposure exposure - The second peak, 100, was 10 times the first peak, 10, but came later after its exposure
- The second peak, 100, was 90 times the first peak, 10, and came sooner after its exposure
- The second peak, 100, matched the first peak, and came sooner after its exposure
- The second peak, 100, was 10 times the first peak, 10, and came sooner after its exposure
Two communities card (model data)
community people immune people A 400 200 B 400 360 Tala reads a card on two communities. Which statement does the card support?
- Community B is 90 percent immune, so a microbe meets fewer people it can spread to
- Community A is better protected, since 200 immune people is a smaller number to protect
- In both communities each immune person is protected alone, so spread is equal
- Community B is fully protected, so each person in it is safe from the microbe
Bacteria count card (model data)
step bacteria bacteria with the resistance trait before the antibiotic 1,000 10 just after the antibiotic 10 10 after regrowth 640 640 Zee reads a count card for bacteria and one antibiotic. Which statement does the card support?
- The person's own cells became resistant to the antibiotic, so 640 bacteria grew back
- The 10 bacteria that remained had the trait before the antibiotic and then multiplied
- The antibiotic gave the resistance trait to the 10 bacteria that remained in the sample
- The antibiotic cleared the viruses too, so just the bacteria with the trait were left

