The cell membrane: a selective barrier
Grade 9 Science Worksheet

Circle the best answer.
Membrane drawing (model, not to scale). No proteins are drawn. Esme lists three particles near a cell: carbon dioxide, potassium ions and glucose. Which can cross the bilayer on its own, with no protein?
- No particle can, because gases need a protein too
- Carbon dioxide, because it has no charge
- Each of the three, because the bilayer is open
- Potassium ions, because they are small
No proteins are drawn. Oxygen, carbon dioxide and chloride ions are outside Bo’s cell. Which one needs a transport protein to cross the bilayer?
Membrane drawing (model, not to scale). A bilayer of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. No proteins are drawn. Outside the cell: 2 oxygen molecules, 2 carbon dioxide molecules and 2 chloride ions. Membrane drawing (model, not to scale). A bilayer of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. No proteins are drawn. Outside the cell: 2 oxygen molecules, 2 carbon dioxide molecules and 2 chloride ions. Membrane drawing (model, not to scale) watery fluid outside the cell oxygen molecules carbon dioxide molecules chloride ions bilayer of phospholipids watery fluid inside the cell - Oxygen, because gases need a protein to cross
- Carbon dioxide, because it is the largest of the three
- No particle needs one, because the membrane is open
- Chloride ions, because they carry a charge
Read this first
Use this
Membrane drawing (model, not to scale). A bilayer of phospholipids. Letter W points to a protein that reaches all the way across the bilayer, with a tunnel shaped to fit potassium ions. Outside the cell: 4 potassium ions.
Potassium ions are outside the cell in Kira’s drawing. Which prediction about how they can cross fits the drawing?
Membrane drawing (model, not to scale). A bilayer of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. Letter W points to a protein that reaches all the way across the bilayer, with a tunnel shaped to fit potassium ions. Outside the cell: 4 potassium ions. Membrane drawing (model, not to scale). A bilayer of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. Letter W points to a protein that reaches all the way across the bilayer, with a tunnel shaped to fit potassium ions. Outside the cell: 4 potassium ions. watery fluid outside the cell K+ K+ K+ K+ W watery fluid inside the cell - Through W, because the tunnel shields them from the tails
- Over the top of W, because proteins stay on the surface
- Nowhere, because the membrane is a solid wall
- Between the tails, because small ions slip through
Membrane drawing (model, not to scale). Phospholipid heads face the watery fluid on both sides of the membrane. Jun wants to know why. Which explanation fits?
Membrane drawing (model, not to scale). A strip of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. The round heads of both rows touch the watery fluid, and the thin tails meet in the middle. Letter H points to one round head in the top row. Letter T points to the two thin tails hanging from it. Membrane drawing (model, not to scale). A strip of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. The round heads of both rows touch the watery fluid, and the thin tails meet in the middle. Letter H points to one round head in the top row. Letter T points to the two thin tails hanging from it. watery fluid outside the cell watery fluid inside the cell H T phospholipids - The heads are water-fearing, so they stay near the water
- The heads are water-loving, so they form hydrogen bonds with water
- The membrane is a solid wall, so heads are pressed outward
- The tails are water-loving, so they pull the heads outward
Use this
Phospholipids in water (model, not to scale). Each phospholipid has one round head and two thin tails. Water fills the space above and below a double layer of phospholipids.
Luz reads that phospholipids placed in water form a double layer. Which prediction describes how the two layers line up?
- Heads face the water on both sides; tails meet in the middle
- Heads and tails lock together in one solid layer
- Tails face the water on both sides; heads meet in the middle
- Heads face the water above; tails face the water below
Membrane drawing in two steps (model, not to scale). Noah reads about a protein that binds one glucose molecule, changes shape and releases the glucose inside the cell. What kind of protein is it?
Membrane drawing in two steps (model, not to scale). Letter M points to a protein that reaches all the way across the bilayer. Step 1: the protein has a cup open to the fluid outside the cell, and 1 glucose molecule sits in the cup. Step 2: the protein has changed shape, and the cup is open to the fluid inside the cell with the glucose molecule released. Membrane drawing in two steps (model, not to scale). Letter M points to a protein that reaches all the way across the bilayer. Step 1: the protein has a cup open to the fluid outside the cell, and 1 glucose molecule sits in the cup. Step 2: the protein has changed shape, and the cup is open to the fluid inside the cell with the glucose molecule released. Step 1 Step 2 fluid outside the cell fluid inside the cell 1 glucose molecule glucose molecule M - A surface protein, which rests on top of the bilayer
- A channel protein, which forms an open tunnel for glucose
- A carrier protein, which changes shape to carry glucose
- A phospholipid, which lets sugars slip through the tails
Use this
Membrane drawing (model, not to scale).
Pia’s drawing shows a protein that reaches across the bilayer and forms a tunnel shaped to fit sodium ions. What kind of protein is it?
Membrane drawing (model, not to scale). Letter N points to a protein that reaches all the way across the bilayer and has an open tunnel through its middle, shaped to fit sodium ions. Outside the cell: 3 sodium ions. Membrane drawing (model, not to scale). Letter N points to a protein that reaches all the way across the bilayer and has an open tunnel through its middle, shaped to fit sodium ions. Outside the cell: 3 sodium ions. Outside the cell Na Na Na N - A carbohydrate chain, which marks the cell’s outside
- A channel protein, which forms a tunnel for ions
- A carrier protein, which changes shape to carry ions
- A phospholipid, which lets sodium ions slip through
A protein uses ATP energy to move sodium ions out of a cell and potassium ions in. What kind of protein is it, according to Ren’s drawing?
Membrane drawing (model, not to scale). Letter J points to a protein that reaches all the way across the bilayer. The drawing labels ATP energy arriving at the protein, with arrows showing sodium ions moved out of the cell and potassium ions moved into the cell. Outside the cell: 3 sodium ions and 1 potassium ion. Inside the cell: 1 sodium ion and 3 potassium ions. Membrane drawing (model, not to scale). Letter J points to a protein that reaches all the way across the bilayer. The drawing labels ATP energy arriving at the protein, with arrows showing sodium ions moved out of the cell and potassium ions moved into the cell. Outside the cell: 3 sodium ions and 1 potassium ion. Inside the cell: 1 sodium ion and 3 potassium ions. Outside the cell sodium ions potassium ion J ATP energy Inside the cell sodium ion potassium ions - A gap in the tails, which lets ions slip across
- A surface protein, which rests on top of the bilayer
- A pump, which uses ATP energy
- A channel protein, which needs no energy
(model, not to scale). In Zee’s drawing, which protein is a peripheral protein, and why?
Membrane drawing (model, not to scale). A strip of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. Protein M reaches all the way across the strip, touching both fluids. Protein N is attached to the inside surface of the bottom row and does not enter the middle. Membrane drawing (model, not to scale). A strip of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. Protein M reaches all the way across the strip, touching both fluids. Protein N is attached to the inside surface of the bottom row and does not enter the middle. watery fluid outside the cell phospholipids Protein M Protein N watery fluid inside the cell - Neither, because the membrane is a solid wall
- Both, because membrane proteins stay on the surface
- N, because it sits on the surface of the membrane
- M, because it touches both fluids
Letter K points to cholesterol in Ari’s animal cell drawing. Where does it lie, and what does it do?
Membrane drawing of an animal cell (model, not to scale). A strip of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. Letter K points to a small molecule lying in the middle of the strip, alongside the thin tails of the phospholipids. Membrane drawing of an animal cell (model, not to scale). A strip of phospholipids with watery fluid outside the cell above and watery fluid inside the cell below. Letter K points to a small molecule lying in the middle of the strip, alongside the thin tails of the phospholipids. animal cell membrane not to scale watery fluid outside the cell watery fluid inside the cell K - Alongside the phospholipids, helping keep the membrane fluid
- On the outside surface, helping cells recognize each other
- Inside a channel, helping ions cross the bilayer
- Alongside the phospholipids, making the membrane a solid wall

